Search results for "Dynamic force spectroscopy"

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Energy landscapes of ligand-receptor couples probed by dynamic force spectroscopy.

2013

Playing a dominant role in many biochemical processes are the dynamic properties of molecular linkages; examples include cell adhesion, enzyme-catalyzed reactions, and molecular recognition by antibodies. Dynamic force spectroscopy, namely separating molecular bonds under external force ramps has rapidly become a powerful tool to study the rugged energy landscape of noncovalent ligand-receptor bonds. The picture shows a surface and tip-bound pair being pulled apart and the derived potential energy diagram.

ChemistryAnalytical chemistryEnergy landscapeProteinsLigand (biochemistry)LigandsMicroscopy Atomic ForcePotential energyAtomic and Molecular Physics and OpticsDynamic force spectroscopyKineticsMolecular recognitionChemical physicsCovalent bondPhysical and Theoretical ChemistryEnergy (signal processing)Protein BindingChemphyschem : a European journal of chemical physics and physical chemistry
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